{APPRIS} release 2017_08.v24 is out!

We are pleased to announce the launch of the last annotations: http://appris-tools.org

• New APPRIS domain: http://appris-tools.org

The old domains of APPRIS (database, server, and web services) still maintained.

• New release of Ensembl (e90) for the local species.

• Human
• Mouse
• Zebra-fish
• Pig             (new assembly Sscrofa11.1)

• APPRIS-CODE

• APPRIS
• Now the decision of which Matador3D to use is automatic.
• By default, we use Matador3D2 but If we have genome coordinates, then we use Matador3D.
• Bug fixed: although the variant has start/stop codon not found, the correct score of CORSAIR will be printed.
• But the final annotation of APPRIS will be the same. 

• SPADE
• New database with the curated domains of Pfam-A (pfam_201706)

New APPRIS domain

We are pleased to announce the launch of the new domain for APPRIS:
http://appris-tools.org

Don't worry. The old domains of APPRIS (database, server, and web services) still maintained.

APPRIS team

{APPRIS} release 2017_06.v23 is out!

We are pleased to announce the launch of the last annotations: http://appris.bioinfo.cnio.es/

• New release of Ensembl (e88) for the local species.

• New APPRIS annotations using the gene dataset of RefSeq:
• Human       (versions: 108, 107, and 105)
• Mouse        (versions: 106)
• Zebra-fish  (versions: 105)
• Rat             (versions: 106)
• Pig             (versions: 105)
• Chimp        (versions: 104)

• New APPRIS annotations using the UniProt proteome from the gene names:
• Human       (versions: 2017_03, 2016_06)
• Mouse        (versions: 2016_10)
• Zebra-fish  (versions: 2016_10)
• Rat             (versions: 2016_10)
• Pig             (versions: 2017_02)
• Chimp        (versions: 2017_02)

• APPRIS-SERVER
• Bug fixed printing the number of peptides.
• Bug fixed: printing the TMH
• Bug fixed: printing the pop-up annotations of Sequence Browser when the transcript id is too long.
• Print the Matador3D and Matador3D2 residues when the  data-set comes from Ensembl and UniProt/APPRIS, respectively.

• APPRIS-CODE
• Bugs fixed: parsing the SPADE outputs to be saved in the APPRIS databases.
• Matador3D2: updated PDB database (PDB_70_with_pdb_seq).
• Matador3D2 is used in the final decision of APPRIS when the gene set comes from UniProt. Matador3D is used for the rest of the gene sets (Ensembl and RefSeq).
• Bug fixed: getting on consensus section in the THUMP method.

{APPRIS} release 2017_01.v20 is out!

We are pleased to announce the launch of the last annotations: http://appris.bioinfo.cnio.es/

• New release of Ensembl (e87) for all species.
• New annotations for RefSeq human gene data-set (versions 105 and 107 for the assemblies GRCh37 and GRCh38, respectively).
• APPRIS annotations for UniProt human, mouse, zebra-fish, and rat. Proteome versions:
  Human (2016_06)
  Mouse (2016_10)
  Zebra-fish (2016_10)
  Rat (2016_10)

• APPRIS-SERVER:
• Include Advanced Search panel.
• CNIO proteomic evidences (PROTEO) have been included into the SequenceBrowser

• APPRIS-CODE:
• APPRIS:
• Changes in the weight of CORSAIR.
• Changes in the weight of firestar.
• Matador3D v2: Has been included in APPRIS code.
• CORSAIR:
• A variant with "start/stop codons not found" can not to win.